1. Nerdio – $500M – Information Technology

Nerdio, a Chicago-based company specializing in IT automation, raised a significant $500 million equity round, led by General Atlantic. This brings the company’s valuation to $1.2 billion, according to Bloomberg. Though relatively under the radar, Nerdio serves over 15,000 customers across 50 countries. The company is profitable and growing rapidly, with an annual recurring revenue increase of over 85%. Founded in 1998, Nerdio has raised a total of $625 million.

2. Latigo Biotherapeutics – $150M – Biotech

Latigo Biotherapeutics, based in Thousand Oaks, California, raised $150 million in a Series B round. The funds will support the development of non-opioid pain relief treatments, targeting pain at its source. Founded in 2018, Latigo has raised $300 million to date.

3. BuildOps – $127M – Commercial Contracting

Santa Monica’s BuildOps, a software platform for managing construction and maintenance projects, secured $127 million. The platform serves the $300 billion contracting industry, from electricians to HVAC professionals. The round was led by Meritech Capital Partners, bringing BuildOps’ total funding to over $225 million.

4. Curevo – $110M – Biotech

Seattle-based Curevo closed a $110 million Series B round. This funding will help advance its shingles vaccine, which aims to prevent painful skin rashes and long-lasting nerve pain. Founded in 2018, Curevo has raised $196 million.

5. Dataminr – $85M – Analytics

New York’s Dataminr, a leader in real-time event detection, raised $85 million in new funding. The company uses public data signals to detect risks and critical information. Dataminr has raised $1.1 billion to date and is nearing $200 million in annual recurring revenue.

6. Arbor Biotechnologies – $74M – Biotech

Arbor Biotechnologies, a biotech company developing genetic medicines, raised $74 million in Series C funding. Founded in 2016, Arbor has raised nearly $305 million.

7. Ampersand Biomedicines – $65M – Biotech

Boston’s Ampersand Biomedicines secured $65 million in Series B funding for its innovative medicines designed to target diseases at their source. The company has raised $115 million so far.

8. Carbon Arc – $56M – Information Technology

Carbon Arc, a New York-based data company, raised $56 million to provide model-ready structured data.

9. Cardiac Dimensions – $53M – Medical Device

Cardiac Dimensions, based in Kirkland, Washington, raised $53 million to support its minimally invasive heart failure device. This funding will help the company expand internationally and complete U.S. trials.

10. Graphite – $52M – Developer Tools

New York-based Graphite raised $52 million in Series B funding for its code review dashboard platform.